9月23日学术报告:Electrochemiluminescence sensing and imaging of single entities: from biomolecules to cells
报告人:Neso SOJIC 教授,法国波尔多大学
报告时间:2026年9月23日下午16:00开始
报告地点:嘉锡楼413会议室

个人简介:
Neso Sojic,法国波尔多大学教授,博士生导师。1997年博士毕业于法国皮埃尔与玛丽-居里大学,随后在美国得克萨斯大学达拉斯分校从事博士后研究工作,1998年加入国立法国波尔多高等化学与物理学院,2006年晋升为波尔多大学教授。担任美国化学会出版的《Chemical and Biomedical Imaging》期刊的副主编。曾获法国化学学会创新奖、中国科学院院长国际奖学金等荣誉。研究领域包括化学发光、纳米电化学、光电分析与生物成像等,是国际ECL成像领域领军学者。已累计在Nature、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Chem. Sci.、Chem. Commun.和Chem. Eur. J.等发表SCI论文250余篇,论文总引用量超8000次,H指数为60。
报告摘要:
ECL is the light emitted by the excited state of a luminophore upon an electrochemical reaction (i.e. without photo-excitation). The initial electron-transfer reaction occurring at the electrode surface triggers a cascade of reactions involving energetic intermediates that leads to the formation of the excited state and in fine to the photon emission. Thus, ECL crystallizes the beauty and complexity from both electrochemistry and photochemistry. Historically, ECL has progressively evolved from a lab curiosity to a powerful bioanalytical technique with an extremely low background that is successfully used for the clinical diagnostics.
In the last decade, ECL has evolved further to a powerful microscopy method. Various configurations have been developed by playing with the light and the dark in order to see conductive or non-conductive objects, with or without a labeling step. In a first part, the molecular aspects of the ECL process will be discussed with the development of ultrasensitive ECL detection in bioassays. In a second part, new ECL approaches such as surface-confined microscopy and shadow ECL microscopy will be presented to extend the performances of ECL imaging.